I'm a heavy headphone user, and I gotta say this takes the experience to another level. For some context, I am also using Sonarworks for calibration..
My personal favorite room (and it seems this is a trend among other users) is Mix Room B. Ambience and focus have been tweaked to taste.
The sound coming out of this is incredibly useful for working. Like, it's a joy to mix with this, and I've tried a couple others that just feel like carrying a weight due to the problems they introduce in your monitoring. Transients response is good, stereo imaging is on another level, but again, surprisingly natural to the point where your ears will adjust without too much hassle.
Now an interesting thing: Most if not all monitoring systems you can imagine need you to put your ears and brain into it for some time to develop a sense of them and how they translate. Getting to know this one has been a breeze, and the project I'm working on translated very well to other systems. Not 100%, but I'm confident that with more time. Into it, ears will adapt and give even better results.
So far, all I've done is praise, but I just can not do it. These guys have made something remarkable.
If I had to name a con about it, it would be about workflow. Ambience and Focus sliders are great to tweak the rooms, but not having indepent Amb/Focus settings for each room is bad. I would love having the option to use different combinations (and maintain them) according to each space I want to use.
Nothing more to add. Much love.
Ps. Have you devs considered making some brief videos showcasing the surround/atmos workflow on headphones? That would be killer.